No other outcomes were different between groups. Patients with low MEP presented more ICU-AW compared to normal MEP patients (64% vs. Inversely, higher body mass index was associated with higher MEP. Patients with low MEP received more catecholamines (p = 0.04) and a higher duration of mechanical ventilation (p = 0.001). Results: Due to the paucity of data reporting threshold value for expiratory muscle weakness, we considered our median value (47 cmH 2O (IQR 44)) as the threshold value for expiratory muscle weakness group (MEP ≤ 47 cmH 2O) and normal expiratory muscle group (MEP > 47 cmH 2O). MEP diagnostic accuracy to predict ICU-AW (ICU acquired weakness), weaning success and sursvival within 30 days were assessed using expiratory muscle strength as absolute values (cmH 2O), as %predicted values and as %lower limit of normal. Maximal expiratory pressure (MEP) measurement was carried out during spontaneous breathing trial using a manometer with an unidirectional valve. Patients and methods: This study is a secondary analysis of our previously described cohort of 124 patients ventilated for at least 24 h assessed for respiratory muscles function. However, few studies reported potential factors leading to expiratory muscle weakness and its importance on weaning success or survival after mechanical ventilation. Several authors stated these muscles importance in cough capacity, contractile efficiency of the diaphragm or reduction of hyperinflation. Rationale: Expiratory muscles has recently been stated as the «neglected component» in mechanically ventilated patient.
Correspondence: Yann Combret Intensive Care 2020, 10 (Suppl 1):COK-1
0 kommentar(er)
